Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome

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Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome

PURPOSE This study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children. METHODS This prospective observational study was conducted in the pediatric neurology ward of Soetomo Hospital. Cases of AES with ages ranging from 1 month to 12 years were included. Cases that were categorized as simpl...

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Neuron-specific enolase concentrations in serum in benign liver diseases.

Neuron-specific enolase (EC 4.2.1.11; NSE), a glycolytic enzyme produced by neuronal and neuroendocrine cells, is used as a tumor marker of neuroendocrine cancers, especially small-cell lung cancer. We have evaluated the behavior of NSE in nonmalignant liver diseases in 161 patients who underwent a thorough clinical and biochemical evaluation. Nine of the 161 patients (5.6%)--three of the 86 ci...

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Serum Neuron-Specific Enolase in Lead-Exposed Individuals.

The article by Ravibabu, et al, 1 provides important new data in the field of biomarkers to monitor exposures to lead within the workplace, as in the lead acid battery manufacturing. They found that the serum neuron-specific enolase (NSE) levels are not elevated in association with concentrations of blood lead levels among workers in the lead acid battery manufacturing plant. In our (unpublishe...

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Rapid electrophoretic determination of neuron-specific enolase isoenzymes in serum.

This assay procedure for each of the two neuron-specific enolases (alpha gamma and gamma gamma) and the non-neuronal enolase (alpha alpha) in serum involves two steps: electrophoretic separation of the three isoenzymes--alpha alpha, alpha gamma, and gamma gamma--on cellulose acetate, and bioluminescence measurement of total enolase activity. From these data, the activity concentrations (U/L) of...

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ژورنال

عنوان ژورنال: Korean Journal of Pediatrics

سال: 2017

ISSN: 1738-1061,2092-7258

DOI: 10.3345/kjp.2017.60.9.302